Network features suggest new hepatocellular carcinoma treatment strategies

Preclinical studies of 166Ho-chitosan for treatment of hepatocellular carcinoma

Introduction: Recently, due to the special characteristics of 166Ho and chitosan, 166Ho-chitosan complex was developed for treatment of tumors such as hepatocellular carcinoma. This complex has been lately prepared with high radiochemical purity in our lab. The preclinical studies of the complex however should be performed to evaluate the tracer concentration in target and...

Icteric type hepatocellular carcinoma: clinical features, diagnosis and treatment.

Icteric type hepatocellular carcinoma (HCC), a clinical entity of HCC presenting as obstructive jaundice caused by floating tumor debris in common bile duct, is rare. Taiwan has a high incidence of HCC and liver cirrhosis. The clinical features, diagnosis and treatment of this disease entity were reviewed. Not all patients with this disease were terminally ill. With proper management and good p...

Multimodal treatment strategies in patients undergoing surgery for hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) is one of the major health problems worldwide, and continues to grow because of its association with hepatitis B and C viruses. In patients with HCC, liver transplantation (LT) and liver resection are the only two curative treatment options. LT remains the best option since it not only removes the tumor, but also the underlying disease. The prerequisite for long-t...

Surgical Treatment Strategies and Prognosis of Hepatocellular Carcinoma

New strategies in hepatocellular carcinoma: genomic prognostic markers.

Accurate prognosis prediction in oncology is critical. In patients with hepatocellular carcinoma (HCC), unlike most solid tumors, the coexistence of two life-threatening conditions, cancer and cirrhosis, makes prognostic assessments difficult. Despite the usefulness of clinical staging systems for HCC in routine clinical decision making (e.g., Barcelona-Clinic Liver Cancer algorithm), there is ...